• As long as developing world

  2019-04-19

  

  As long as developing-world health systems are ill prepared to offer safe anaesthesia and intensive care to patients in need of surgery, surgically treatable conditions will remain leading causes of death, the world will lose trillions of dollars in gross domestic product, and we in the global heal

• br Material and methods br Results br Discussion

  2019-04-19

  

  Material and methods Results Discussion The present study provides clinical, molecular, and in vitro electro-physiological evidence that a rare SNP (KCNE1-D85N) can act as a genetic modifier in LQTS. In general, SNPs are thought to be non-pathological, but some have been reported to modify

• All patients with symptomatic cardiac AL amyloidosis

  2019-04-19

  

  All 4 patients with symptomatic cardiac AL amyloidosis had poor prognoses. The median survival period for these 4 patients was 12.3 months (minimum=4 months, maximum=28 months) (Table 1). The patient in Case 2, whose BNP level was the highest of the 4 patients, had the shortest survival period. Howe

• pten pathway Complete resection of the tumor with negative m

  2019-04-19

  

  Complete resection of the tumor with negative margins at the time of diagnosis appears the most preferred mode of intervention towards favorable prognosis. It is worth mentioning that the germline pten pathway of DICER1 is believed as the genetic cause in the majority of PPB; consequently, earlier d

• br Authors disclosure Mark Clemons received honoraria for ta

  2019-04-19

  

  Authors\' disclosure Mark Clemons received honoraria for talks from Novartis and Amgen, research funding from Novartis. Case In September 2007 a 9½-year-old boy was diagnosed with a Ewing sarcoma (EWS-FL1 translocation positive) of the right scapula. MRI showed a tumor of 8.0×2.9 ×6.2cm locat

• order Laminin 925-933 br Grant support This work was

  2019-04-19

  

  Grant support This work was supported by INSERM, the “Ligue Contre le Cancer” (Equipe Labellisée LIGUE 2012; grant EL2012NCC/DH), the “Fédération Nationale Enfants et Santé” and the “Société Française de lutte contre les Cancers et les leucémies de l\'Enfant et de l\'Adolescent(“appel à projet 20

• br Commentary Careful analysis of

  2019-04-19

  

  Commentary Careful analysis of the electrocardiograph (Fig. 1) reveals narrow and similar QRS complexes in all the beats, showing that they are all intrinsic QRS complexes. Some intrinsic P waves are also visible at the ST-T segment (after R3, R7, R11, and R15); these are the beats without any sp

• This Ca overload activates the forward mode of the

  2019-04-19

  

  This Ca2+ overload activates the forward mode of the Na+/Ca+ exchanger (NCX), increases the transient inward current (Iti), and induces ventricular arrhythmias due to delayed after depolarizations (DADs). Subtypes of CPVT Several subtypes of CPVT have been reported (Table 1). The most common typ

• Perteneciente a la representaci n que

  2019-04-19

  

  Perteneciente s6 kinase la representación que Hanumān realiza del , Acosta emplea un apto neologismo, el de “hu-mono” (171). Con este término se enfatiza hasta qué punto el narrador y el mono son reflejos el uno del otro. El salto físico del mono gramático inspira otros saltos en el lenguaje de Paz.

• La ignorancia que evidencia Xa Am rica po tica

  2019-04-19

  

  La ignorancia que evidencia Xa. América poética respecto de los literatos mexicanos corrobora la falta de proximidad entre zonas tan distantes del orbe hispanoamericano. Al mismo tiempo comprueba el vacío biográfico que en este punto muestran las revistas mexicanas o, más exactamente, El Recreo de l

• The congruence between BrS and

  2019-04-18

  

  The congruence between BrS and ERS with respect to clinical manifestations and response to therapy lends further support to the repolarization hypothesis. Using an experimental model of ERS, Koncz et al. [30]. recently provided evidence in support of the hypothesis that, similar to the mechanism ope

• The measurement of the PPI

  2019-04-18

  

  The measurement of the PPI of DP following entrainment pacing usually consists of measuring the interval between the last capturing stimulus and the next DP. This technique is generally based on the assumption that, in the presence of 1:1 capture, pacing depolarizes the zone of slow conduction in th

• Aggressive osteoblastoma is characterized by epithelioid ost

  2019-04-18

  

  Aggressive osteoblastoma is characterized by epithelioid osteoblasts that are, two to three times larger than conventional osteoblasts, and have abundant eosinophilic cytoplasm, large vesicular eccentric round to oval nuclei with prominent nucleoli. Usually there are rare or absence of mitoses and i

• Our analysis also showed that there were no

  2019-04-18

  

  Our analysis also showed that there were no meaningful lipid changes with anastrozle, as a surrogate for cardiovascular health. This is in keeping with the TEAM Japan [17], TEAM Greek [18] sub-studies and the SABRE trial [19], which showed that AIs have no detrimental effects on lipid parameters. Th

• Asimismo y con distinto nfasis entre s estas cr

  2019-04-18

  

  Asimismo y con distinto énfasis entre sí, estas crónicas presentan la dimensión de la escritura de la historia como reparación, como sutura del trauma, y también como espacio textual único para la supervivencia de memorias en constante proceso de desaparición. Esto les confiere cierto ubicuo tono de

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