• Introduction Cardiac resynchronization therapy CRT reduces m

  2019-05-13

  

  Introduction Cardiac resynchronization therapy (CRT) reduces mortality and morbidity in selected heart failure patients with impaired left ventricular (LV) function and cardiac dyssynchrony [1]. Most patients receive CRT with a defibrillator (CRT-D) because the indications for an implantable cardio

• Introduction Leukaemias lymphomas and multiple myeloma can b

  2019-05-13

  

  Introduction Leukaemias, lymphomas and multiple myeloma can be the dreadful sequelae of viral infections. RNA oncogenic viruses, which are also known as retroviruses, were initially known to cause lymphoproliferative disorders only in animals, but have also been reported to demonstrate their transf

• br Current approaches to HIV prevention typically target peo

  2019-05-13

  

  Current approaches to HIV prevention typically target people who are identified as, or self-identify, with being at risk. In Africa, 74% of new HIV infections are among adolescent girls aged 15–19 years, and AIDS-related illnesses are the leading cause of death among adolescent girls and women of

• In summary we present a rare

  2019-05-13

  

  In summary, we present a rare case of magnesium sulfate-induced fetal bradyarrhythmia caused by prolongation of the refractory period of the atrioventricular node in the case of blocked premature atrial contractions. Clinicians should consider fetal bradyarrhythmia when the baseline fetal heart rate

• br Conclusions br Study limitations br Conflict of interest

  2019-05-13

  

  Conclusions Study limitations Conflict of interest Introduction Dabigatran etexilate, an orally administered pro-drug, is rapidly converted by a serum esterase to dabigatran, a potent, direct, and competitive inhibitor of thrombin. It has an absolute bioavailability of 6.5% and a serum c

• LQT can have numerous clinical manifestations ranging from n

  2019-05-10

  

  LQT1 can have numerous clinical manifestations, ranging from no symptoms to sudden cardiac death, which reflects the heterogeneity in channel dysfunction. Mutation type, location, and even a patient׳s ethnic background, age, and gender are critical factors that affect the pathophysiology of the dise

• Case reports br Discussion RV perforation is a

  2019-05-10

  

  Case reports Discussion RV perforation is a rare but serious complication of PPM and ICD implantation. It is diagnosed when at least the tip of a passive fixation lead or the screw of an active fixation lead passes through the myocardium and extends into the pericardial cavity [1]. This complica

• br It is encouraging to read in the Article by

  2019-05-10

  

  It is encouraging to read in the Article by Mercy Kanyuka and colleagues (March, 2016) about Malawi\'s success in reducing child mortality, but I fear the authors might have missed one of the key factors contributing towards this great achievement. Specifically, that Malawi is unique in sub-Sahara

• br Discussion Our case demonstrates feasibility for improvem

  2019-05-10

  

  Discussion Our case demonstrates feasibility for improvement in erythropoiesis in a patient with poor predictor of ESA/G-CSF response/growth factor refractory, low-risk MDS who was treated with sertraline for co-morbid depression. Within 100 days concurrent administration of sertraline, ESA and G

• PD 0332991 Nowadays other Brazilian HIV patients were enroll

  2019-05-09

  

  Nowadays other 20 Brazilian HIV+ patients were enrolled in the second-phase of Lu et al. clinical trial [3], and biologic samples are becoming available for novel investigation. All this considered and taken into account that the intrinsic ability of each HIV+ individual to counteract HIV-1 result

• Biological mechanisms have also been associated with poor ca

  2019-05-09

  

  Biological mechanisms have also been associated with poor cardiovascular outcomes in ICD patients with depression, such as alteration of cardiac autonomic tone, activation of the sympathetic nervous system, enhanced activity of the hypothalamic-pituitary-adrenal axis, and elevated inflammatory and p

• br Genetic basis Similar to other arrhythmia syndromes Bruga

  2019-05-09

  

  Genetic basis Similar to other arrhythmia syndromes, Brugada and early repolarization syndromes are inherited diseases that are usually transmitted in an autosomal-dominant manner [26]. To date, 13 genes have been associated with Brugada syndrome. Loss-of-function mutations in SCN5A, encoding the

• br Conflict of interest br Introduction Landiolol

  2019-05-09

  

  Conflict of interest Introduction Landiolol is an intravenous short-acting beta-adrenoreceptor blocker, and its wide use is exhibited by rapid wash out and a less-sustained effect on cardiac function after decreasing the dose or stopping its administration [1]. We present a patient with drug-r

• cmv virus I am delighted to introduce the inaugural issue of

  2019-05-09

  

  I am delighted to introduce the inaugural issue of . It is very likely that you are reading this online, this being an online-only journal, although we have also printed this first issue in order to showcase the journal to readers of . What is certain is that, in accessing this article, and all the

• br The past decade has seen increasing

  2019-05-09

  

  The past decade has seen increasing global policy attention to nutrition. Concrete steps have been taken to construct a global governance architecture for nutrition and also to mobilise resources for action. Efficacious, low-cost interventions exist, and there is greater consensus around technical

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